ICCD speckle observations of binary stars. IV - Measurements during 1986-1988 from the Kitt Peak 4 M telescope One thousand five hundred and fifty measurements of 1006 binary starsystems observed mostly during 1986 through mid-1988 by means of speckleinterferometry with the KPNO 4-m telescope are presented. Twenty-onesystems are directly resolved for the first time, including newcomponents to the cool supergiant Alpha Her A and the Pleiades shellstar Pleione. A continuing survey of The Bright Star Catalogue yieldedeight new binaries from 293 bright stars observed. Corrections tospeckle measures from the GSU/CHARA ICCD speckle camera previouslypublished are presented and discussed.